<?xml version="1.0"?>
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/GO_0003865 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0003865">
        <rdfs:label>3-oxo-5-alpha-steroid 4-dehydrogenase activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0035671 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0035671">
        <rdfs:label>enone reductase activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0047751 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0047751">
        <rdfs:label>3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0003865"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0035671"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/25314</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/28199</ns3:IAO_0000233>
        <oboInOwl:hasDbXref>MetaCyc:RXN-711</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>3-oxosteroid 5alpha-reductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasNarrowSynonym>cholestenone 5-alpha-reductase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasBroadSynonym>steroid 5alpha-hydrogenase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>steroid 5alpha-reductase</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasNarrowSynonym>progesterone 5-alpha-reductase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:id>GO:0047751</oboInOwl:id>
        <oboInOwl:hasDbXref>KEGG_REACTION:R02610</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:21952</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>testosterone delta4-hydrogenase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>MetaCyc:RXN-4229</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:69987</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:50816</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the reaction: 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-delta(4)-steroid + H+ + NADPH.</ns3:IAO_0000115>
        <oboInOwl:hasBroadSynonym>sterol 5-alpha reductase activity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>MetaCyc:1.3.99.5-RXN</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:54416</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:24552</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EC:1.3.1.22</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasNarrowSynonym>cholestenone 5alpha-reductase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>RHEA:69991</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:50820</oboInOwl:hasDbXref>
        <oboInOwl:hasBroadSynonym>3-oxosteroid delta4-dehydrogenase</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasNarrowSynonym>cholestenone 5a-reductase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>RHEA:54384</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:84191</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:84195</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>testosterone 5alpha-reductase</oboInOwl:hasNarrowSynonym>
        <skos:exactMatch rdf:resource="http://identifiers.org/metacyc.reaction/1.3.99.5-RXN"/>
        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/CHOLESTENONE-5-ALPHA-REDUCTASE-RXN"/>
        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/RXN-4229"/>
        <skos:narrowMatch rdf:resource="http://identifiers.org/metacyc.reaction/RXN-711"/>
        <skos:exactMatch rdf:resource="http://purl.uniprot.org/enzyme/1.3.1.22"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/21952"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/24552"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/50816"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/50820"/>
        <skos:exactMatch rdf:resource="http://rdf.rhea-db.org/54384"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/54416"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/69987"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/69991"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/84191"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/84195"/>
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