L-lysine biosynthetic process obsolete L-lysine biosynthetic process via alpha-aminoadipate and saccharopine https://github.com/geneontology/go-ontology/issues/30820 https://github.com/geneontology/go-ontology/issues/31525 true biological_process GO:0051975 OBSOLETE. The chemical reactions and pathways resulting in the formation of L-lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine. lysine biosynthesis via aminoadipic acid and saccharopine The reason for obsoletion is that this term represents a GO-CAM model. lysine biosynthetic process via aminoadipic acid and saccharopine