part of type I interferon-mediated signaling pathway type I interferon signaling pathway biological_process type I interferon-activated signaling pathway GO:0060337 Reactome:R-HSA-909733 The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. cellular response to type I interferon interferon-mediated signaling pathway