growth hormone receptor signaling pathway growth hormone receptor signaling pathway via JAK-STAT biological_process Reactome:R-HSA-982772 GO:0060397 The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. JAK-STAT cascade involved in growth hormone signalling pathway