ubiquitin-protein transferase activity ubiquitin protein ligase activity Reactome:R-HSA-3322429 Reactome:R-HSA-9686969 Reactome:R-HSA-9755304 GO:0090622 Reactome:R-HSA-5682858 Reactome:R-HSA-183036 EC:2.3.2.27 EC:2.3.2.26 Reactome:R-HSA-9011300 Reactome:R-HSA-9948362 Reactome:R-HSA-9932512 Reactome:R-HSA-9932510 Reactome:R-HSA-8854041 This enzyme catalyzes a transferase reaction. EC:2.3.2.36 Reactome:R-HSA-8866546 EC:2.3.2.33 Reactome:R-HSA-6782943 EC:2.3.2.31 Reactome:R-HSA-8956026 Reactome:R-HSA-69015 Reactome:R-HSA-9706354 Reactome:R-HSA-5684071 Reactome:R-HSA-8948832 Reactome:R-HSA-9759172 GO:1904264 Reactome:R-HSA-9706356 Reactome:R-HSA-8953946 Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. Reactome:R-HSA-8848829 Reactome:R-HSA-5246693 GO:1904822 Reactome:R-HSA-5658424 Reactome:R-HSA-8939335 Reactome:R-HSA-201445 Reactome:R-HSA-6798373 Reactome:R-HSA-6781867 Reactome:R-HSA-9733316 Reactome:R-HSA-5687081 Reactome:R-HSA-8942101 Reactome:R-HSA-5654677 Reactome:R-HSA-5654679 Reactome:R-HSA-6790487 Reactome:R-HSA-5654672 Reactome:R-HSA-8938773 E3 Reactome:R-HSA-5610737 Reactome:R-HSA-4608852 2014-05-18T09:11:21Z Reactome:R-HSA-9931430 Reactome:R-HSA-8875431 Reactome:R-HSA-8938815 Reactome:R-HSA-9759154 Reactome:R-HSA-9009403 dph Reactome:R-HSA-6804441 Reactome:R-HSA-936462 ubiquitin ligase activity Reactome:R-HSA-9766645 Reactome:R-HSA-8943040 Reactome:R-HSA-6804724 Reactome:R-HSA-9708517 Reactome:R-HSA-4641159 Reactome:R-HSA-934604 Reactome:R-HSA-5654684 Reactome:R-HSA-9755505 Reactome:R-HSA-9021523 Reactome:R-HSA-8854051 Reactome:R-HSA-8866856 GO:0090302 Reactome:R-HSA-9686920 Reactome:R-HSA-8876258 Reactome:R-HSA-9946390 Reactome:R-HSA-6804253 Reactome:R-HSA-9009308 Reactome:R-HSA-936475 Reactome:R-HSA-9033485 Reactome:R-HSA-8851011 Reactome:R-HSA-5632648 Reactome:R-HSA-5690827 Reactome:R-HSA-4641246 Reactome:R-HSA-1225956 Reactome:R-HSA-9705738 Reactome:R-HSA-4641129 protein ubiquitination activity Reactome:R-HSA-9931298 Reactome:R-HSA-6807106 Reactome:R-HSA-8952382 Reactome:R-HSA-8854628 Reactome:R-HSA-9929490 ER-associated E3 ligase Reactome:R-HSA-6804942 Reactome:R-HSA-4641253 Reactome:R-HSA-8952419 Reactome:R-HSA-1504190 Reactome:R-HSA-5635864 Reactome:R-HSA-8875183 Reactome:R-HSA-8867288 Reactome:R-HSA-990526 Reactome:R-HSA-8877003 Reactome:R-HSA-6807134 GO:0061630 Reactome:R-HSA-9954737 Reactome:R-HSA-6804879 Reactome:R-HSA-5674022 Reactome:R-HSA-9945766 molecular_function Reactome:R-HSA-9762091 Reactome:R-HSA-5635856 Reactome:R-HSA-3640861 Reactome:R-HSA-9008076 Reactome:R-HSA-68946 Reactome:R-HSA-8939706 Reactome:R-HSA-5689111 Reactome:R-HSA-8943080 Reactome:R-HSA-8956684 Reactome:R-HSA-8948775 Reactome:R-HSA-6785361 Reactome:R-HSA-9604629 Reactome:R-HSA-9685195 Reactome:R-HSA-8943003 ubiquitin-like protein ligase activity