ubiquitin-protein transferase activity ubiquitin conjugating enzyme activity https://github.com/geneontology/go-ontology/issues/30261 dph EC:2.3.2.24 EC:2.3.2.23 2014-05-18T09:25:19Z HECT E3 EC:2.3.2.25 molecular_function GO:0061631 E2 Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y = Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. ubiquitin-like protein conjugating enzyme activity