O-methyltransferase activity RNA methyltransferase activity RNA 2'-O-methyltransferase activity https://github.com/geneontology/go-ontology/issues/30193 Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide. RHEA:65380 dph 2019-01-23T14:23:00Z molecular_function RHEA:58956 RHEA:56884 GO:0062105 RHEA:42724 RHEA:48628