Shc-Grb2-Sos complex 2009-04-29T04:30:00Z GO:0070619 cellular_component A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. Shc-Grb2-mSos1 complex, EGF stimulated mah plasma membrane protein complex