EGFR-Shc-Grb2-Sos complex GO:0070621 2009-04-29T04:38:10Z A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. mah cellular_component plasma membrane protein complex