part of protein-RNA complex assembly regulatory ncRNA-mediated gene silencing RISC complex assembly https://github.com/geneontology/go-ontology/issues/22653 biological_process 2009-09-11T03:57:38Z miRNA loading onto RISC GO:0070922 GO:0070923 GO:0035280 The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA. siRNA loading onto RISC involved in gene silencing by small RNA miRISC assembly GO:0035087 siRNA loading onto RISC involved in RNA interference mah gene silencing by RNA, small RNA loading onto RISC RISC assembly small RNA loading onto RISC