part of cell cycle process nuclear DNA replication protein-DNA complex assembly DNA replication preinitiation complex assembly https://github.com/geneontology/go-ontology/issues/10596 biological_process GO:1902293 The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity. mah GO:0071163 GO:1902316 DNA replication preinitiation complex formation pre-IC complex assembly 2009-11-19T11:13:41Z