part of protein quality control for misfolded or incompletely synthesized proteins proteasome-mediated ubiquitin-dependent protein catabolic process cellular response to misfolded protein nuclear protein quality control by the ubiquitin-proteasome system https://github.com/geneontology/go-ontology/issues/26433 nucleus-associated proteasomal ubiquitin-dependent protein breakdown nucleus-associated proteasomal ubiquitin-dependent protein degradation GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolism ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome A protein quality control pathway that results in the breakdown of misfolded, damaged or unassembled proteins via a mechanism in which the proteins are ubiquitinated, and then targeted to nuclear proteasomes for degradation. 2010-02-11T03:31:46Z mah biological_process