part of vacuolar membrane guanyl-nucleotide exchange factor complex Ragulator complex https://github.com/geneontology/go-ontology/issues/20822 https://github.com/geneontology/go-ontology/issues/21777 https://github.com/geneontology/go-ontology/issues/23917 GTPase-containing complex for Gap1p sorting in the endosome GO:0034448 GO:0034449 GO:0071986 EGO-GSE complex mah 2010-10-22T02:42:13Z Rag GEF cellular_component A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signaling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified). EGO complex GSE complex MAPKSP1/ROBLD3/C11orf59 complex membrane protein complex