negatively regulates metanephros development biological regulation regulation of metanephros development negative regulation of metanephros development 2010-03-18T01:45:48Z biological_process GO:0072217 mah Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. negative regulation of kidney development