part of proximal convoluted tubule segment 1 development metanephric proximal convoluted tubule development metanephric proximal convoluted tubule segment 1 development mah metanephric S1 development biological_process GO:0072231 The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. 2010-03-18T03:39:10Z