obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane true OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane jl biological_process GO:0075705 2009-04-23T02:08:06Z This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis. viral penetration via endocytosis followed by genetic injection through the endosome membrane