negatively regulates regulation of oxidative phosphorylation oxidative phosphorylation biological regulation negative regulation of oxidative phosphorylation GO:0090324 tb Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. 2010-05-14T10:21:33Z biological_process negative regulation of cellular respiration