cysteine-type endopeptidase activity obsolete cysteine-type endopeptidase activity involved in apoptotic signaling pathway https://github.com/geneontology/go-ontology/issues/28468 true 2011-12-12T01:43:00Z OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. GO:0097199 initiator caspase activity pr activator caspase activity Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases. The reason for obsoletion is that this term represents a GO-CAM model. apical caspase activity cysteine-type endopeptidase activity involved in apoptotic signalling pathway molecular_function