part of apoptotic signaling pathway mitochondrial outer membrane permeabilization The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. 2012-06-19T04:06:54Z MOMP GO:0097345 mitochondrial outer membrane permeabilization during apoptotic cell death mitochondrion outer membrane permeabilization pr BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively). biological_process positive regulation of mitochondrial membrane permeability involved in apoptotic process