receptor-mediated bacteriophage irreversible attachment to host cell The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell. phage irreversible adsorption biological_process bm irreversible bacteriophage attachment, binding of host cell surface receptor GO:0098002 entry receptor-mediated virion attachment to host cell