tRNA (uridine) methyltransferase activity tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity https://github.com/geneontology/go-ontology/issues/24975 https://github.com/geneontology/go-ontology/issues/30193 molecular_function RHEA:43208 2020-10-27T21:34:30Z GO:0106335 Catalysis of the reaction: 5-(carboxymethyl)uridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine. The methylation occurs on the modified base. EC:2.1.1.229 hjd