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    <!-- 
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    <!-- http://purl.obolibrary.org/obo/GO_0052689 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0052689">
        <rdfs:label>carboxylic ester hydrolase activity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0106435 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0106435">
        <rdfs:label>carboxylesterase activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0052689"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/21843</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/30193</ns3:IAO_0000233>
        <oboInOwl:hasDbXref>RHEA:47360</oboInOwl:hasDbXref>
        <oboInOwl:id>GO:0106435</oboInOwl:id>
        <oboInOwl:hasDbXref>RHEA:47364</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9749647</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EC:3.1.1.1</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>triacetin esterase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:created_by>hjd</oboInOwl:created_by>
        <oboInOwl:hasDbXref>RHEA:31779</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>vitamin A esterase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>RHEA:47392</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:50136</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:47352</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:59388</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>cocaine esterase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>RHEA:21164</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:47356</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9619024</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:50148</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:38555</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:50144</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>nonspecific carboxylesterase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasNarrowSynonym>alpha-carboxylesterase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>serine esterase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>B-esterase activity</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>procaine esterase</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>RHEA:47388</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RHEA:47348</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>RHEA:63052</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-9727567</oboInOwl:hasDbXref>
        <rdfs:comment>Note: This covers a broad range of specificity; also hydrolyzes vitamin A esters.</rdfs:comment>
        <oboInOwl:hasRelatedSynonym>ali-esterase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>MetaCyc:CARBOXYLESTERASE-RXN</oboInOwl:hasDbXref>
        <oboInOwl:creation_date>2022-10-03T21:37:41Z</oboInOwl:creation_date>
        <skos:exactMatch rdf:resource="http://purl.uniprot.org/enzyme/3.1.1.1"/>
        <skos:exactMatch rdf:resource="http://rdf.rhea-db.org/21164"/>
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        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/38555"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47348"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47352"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47356"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47360"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47364"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47388"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/47392"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/50136"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/50144"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/50148"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/59388"/>
        <skos:narrowMatch rdf:resource="http://rdf.rhea-db.org/63052"/>
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