hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides RNA NAD+-cap (NAD+-forming) hydrolase activity https://github.com/geneontology/go-ontology/issues/17594 https://github.com/geneontology/go-ontology/issues/27180 https://github.com/geneontology/go-ontology/issues/30193 Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+. molecular_function GO:0110152 kmv 2019-07-08T15:55:11Z RNA NAD-cap (NAD-forming) hydrolase activity This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. RHEA:60880 catalytic activity, acting on RNA