DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex DNA gyrase complex https://github.com/geneontology/go-ontology/issues/15575 https://github.com/geneontology/go-ontology/issues/17736 krc topoisomerase II complex cellular_component 2019-08-20T18:36:35Z GO:0120217 A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).