negatively regulates negative regulation of cell cycle process oocyte karyosome formation biological regulation regulation of oocyte karyosome formation negative regulation of oocyte karyosome formation https://github.com/geneontology/go-ontology/issues/21298 2021-04-19T21:39:47Z krc Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. GO:0120314 biological_process negative regulation of reproductive process negative regulation of chromosome organization