carboxylic ester hydrolase activity FAHFA hydrolase activity https://github.com/geneontology/go-ontology/issues/31722 RHEA:52048 RHEA:52068 RHEA:52092 molecular_function RHEA:52056 RHEA:52076 RHEA:52096 RHEA:52052 RHEA:52072 GO:0120573 sjm Catalysis of the hydrolysis of the ester bond in a fatty acid ester of a hydroxy fatty acid (FAHFA), yielding a free fatty acid and a hydroxy fatty acid. FAHFAs are a class of endogenous bioactive signaling lipids in which a fatty acid is esterified to a hydroxyl group on a second fatty acid backbone. RHEA:52080 fatty-acid ester of hydroxy-fatty-acid hydrolase activity 2026-03-13T16:05:52Z RHEA:52064 RHEA:52084 RHEA:52060