phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating N-formyl peptide-activated signaling pathway https://github.com/geneontology/go-ontology/issues/27490 A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by an N-formyl peptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. chemotaxis. N-formyl peptides include N-formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe), an N-formylated tripeptide sometimes simply referred to as chemotactic peptide. fMLF is a potent polymorphonuclear leukocyte (PMN) chemotactic factor and is also a macrophage activator. biological_process fMLP-activated G protein-coupled receptor signaling pathway pg GO:0140307 2025-10-20T14:16:02Z