part of has part creatine kinase activity metabolic process phosphoamidase activity futile creatine cycle https://github.com/geneontology/go-ontology/issues/21517 2021-05-26T06:40:18Z pg The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis. GO:0140651 biological_process adaptive thermogenesis