detoxification detoxification of endogenously produced metabolite https://github.com/geneontology/go-ontology/issues/22413 https://github.com/geneontology/go-ontology/issues/31336 GO:0140729 prevention of self-toxicity A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme. self-resistance to endogenously produced toxin 2021-11-24T06:32:14Z self-resistance to endogenously produced compound pg biological_process self-resistance to bioactive secondary metabolite self-resistance to endogenously produced metabolite