programmed DNA elimination programmed DNA elimination by elimination of internal DNA segments https://github.com/geneontology/go-ontology/issues/22815 A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates. biological_process pg 2022-02-07T09:49:18Z GO:0140763