molecular_function pore-forming activity https://github.com/geneontology/go-ontology/issues/24007 pinholin activity GO:0140911 holin activity canonical holin activity An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. 2022-09-19T13:07:10Z TC:1.C GO:0034292 GO:0034290 pore forming activity GO:0034291 molecular_function pg