disulfide oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor catalytic activity, acting on a protein protein-glutathione oxidoreductase (glutathione) activity https://github.com/geneontology/go-ontology/issues/25498 glutaredoxin activity Catalysis of the reaction: glutathionylated protein (PSSG) + glutathione (GSH) = protein-thiol (PSH) + glutathione disulfide (GSSG). The reaction may proceed via a 'monothiol' or 'dithiol' mechanism. 2023-06-07T06:36:33Z pg molecular_function GO:0141049 glutathione oxidoreductase activity