proteasome-mediated ubiquitin-dependent protein catabolic process RADAR pathway https://github.com/geneontology/go-ontology/issues/31570 A quality control pathway that degrades peroxisomal matrix protein receptors when the recycling machinery is blocked. When recycling to the cytosol fails, cargo-free receptors accumulate at the peroxisomal membrane, where they are polyubiquitinated and subsequently degraded by the ubiquitin-proteasome system (UPS). GO:0170074 ew Receptor Accumulation and Degradation in the Absence of Recycling biological_process 2026-02-17T22:02:27Z