part of outer kinetochore protein-containing complex Knl1/Spc105 complex https://github.com/geneontology/go-ontology/issues/25544 https://github.com/geneontology/go-ontology/issues/31052 Spc105p/Kre28p complex KNL1 complex GO:0180019 A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans, budding and fission yeast, it consists of KNL1/ZWINT, Spc105p/Kre28p and Spc7/Sos1, members of the Panther PTHR28260 and PTHR37329 families, respectively. cellular_component 2023-06-16T09:53:26Z KNL-1 complex vw Spc105 complex