small RNA 2'-O-ribose methyltransferase activity U6 snRNA 2'-O-ribose methyltransferase activity https://github.com/geneontology/go-ontology/issues/25706 https://github.com/geneontology/go-ontology/issues/30193 2023-07-14T13:19:39Z vw Catalysis of the reaction: S-adenosyl-L-methionine + U6 snRNA = S-adenosyl-L-homocysteine + U6 containing a 3'-terminal 2'-O-methylnucleotide + H+. molecular_function GO:0180021 RHEA:63088