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        <ns3:IAO_0000115>A cytoplasmic tRNA surveillance pathway that targets mature hypomodified tRNAs, catalyzed by 5&#39;-3&#39; exonucleases Xrn1 (S. cerevisiae/human) and Rat1 (S. cerevisiae) XRN2 human, and regulated by adenosine 3&#39;,5&#39; bisphosphate (pAp).</ns3:IAO_0000115>
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