intracellular protein-containing complex transferase complex RSP5-BUL ubiquitin ligase complex cellular_component A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation. bhm RSP5-BUL2 complex 2014-03-03T22:53:01Z GO:1990306 This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424 RSP5-BUL1 complex