part of mitotic checkpoint complex nuclear protein-containing complex mitotic checkpoint complex, CDC20-MAD2 subcomplex A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. cellular_component An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay). CDC20-MAD2 complex bhm 2014-03-17T14:11:35Z GO:1990333