has part SUMO activating enzyme complex SUMO ligase complex nuclear protein-containing complex activated SUMO-E1 ligase complex bhm SUMO-SAE1/2 complex 2014-03-31T13:22:45Z A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins. GO:1990354 An example of this is SAE1 in human (UniProt symbol Q9UBE0) in PMID:15660128 (inferred from direct assay). cellular_component