part of germ cell nucleus nuclear protein-containing complex Rhino-Deadlock-Cutoff Complex RDC complex Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation. 2014-08-29T14:08:37Z GO:1990469 An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153. bhm cellular_component rhi-del-cuff complex PET complex