RNA polymerase II transcription regulator complex ATF4-CREB1 transcription factor complex bhm Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway. cellular_component 2014-12-15T14:22:44Z GO:1990589