estradiol estradiol valerate http://id.loc.gov/authorities/subjects/sh95009165 http://purl.bioontology.org/ontology/SNOMEDCT/96350008 http://purl.obolibrary.org/obo/CHEBI_31561 http://purl.obolibrary.org/obo/NCIT_C1090 https://en.wikipedia.org/wiki/Estradiol_valerate https://www.wikidata.org/wiki/Q5401768 EV The parenterally-administered synthetic valerate ester of estradiol. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. estradiol ester therapeutic estradiol