oocyte oocyte maturation http://purl.obolibrary.org/obo/GO_0001556 https://www.wikidata.org/wiki/Q14864725 A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. oocyte development