spermatid development sperm capacitation http://purl.bioontology.org/ontology/MESH/D013075 http://purl.obolibrary.org/obo/GO_0048240 https://www.wikidata.org/wiki/Q14860527 A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. The structural and functional changes by which spermatozoa become capable of oocyte fertilization. It normally requires exposing the sperm to the female genital tract for a period of time to bring about increased sperm motility and the acrosome reaction before fertilization in the fallopian tubes can take place. capacitation of spermatozoa sperm activation