chromosomal intersex condition Swyer syndrome http://homosaurus.org/v2/swyerSyndrome http://purl.bioontology.org/ontology/MESH/D006061 A type of hypogonadism in a person whose karyotype is 46,XY. People with Swyer syndrome are born with the appearance of a normal female in most anatomic respects except that the child has nonfunctional streak gonads instead of ovaries or testes. As their ovaries produce no important body changes before puberty, a defect of the reproductive system typically remains unsuspected until puberty fails to occur. They appear to be normal women and are generally considered so. Swyer's syndrome Swyer-James syndrome allosomal chromosomal syndrome Gerald Swyer