49,XXXYY syndrome http://purl.bioontology.org/ontology/SNOMEDCT/770908007 A rare gonosome anomaly syndrome characterised by a androgynous habitus with gynecoid fat distribution and shape, normal to tall stature, moderate to severe intellectual disability, distinctive facial features (prominent forehead, epicanthic folds, broad nasal bridge, prognathism), gynaecomastia, hypogonadism, cryptorchidism, small penis and behavioural abnormalities (including solitary, passive disposition but prone to aggressive outbursts, autistic). Skeletal malformations, such as delayed bone age, fifth finger clinodactyly, elbow malformations and slow molar development may also be associated. XXXYY syndrome chromosomal gain syndrome 49,XXXYY allosomal chromosomal syndrome