Edwards syndrome 758.2 http://purl.bioontology.org/ontology/MEDDRA/10014273 http://purl.bioontology.org/ontology/MESH/D000073842 http://purl.obolibrary.org/obo/DOID_1085 https://en.wikipedia.org/wiki/Edwards_syndrome https://www.wikidata.org/wiki/Q457737 A chromosome disorder associated with trisomy of all or part of chromosome 18. Clinical manifestations include intrauterine growth retardation; cleft palate; congenital heart defects; microcephaly; micrognathia and clenched fists with overlapping fingers. Most affected fetuses do not survive to birth. Those who survive through their first year often have severe intellectual disability. Edwards syndrome and Patau syndrome Edwards syndrome, unspecified Edwards' syndrome complete trisomy 18 syndrome mosaic trisomy 18 syndrome trisomy 18 syndrome trisomy E syndrome autosomal chromosomal syndrome