human nuclear receptor subfamily 5 group A member 1, mRNA steroidogenic factor 1 http://purl.bioontology.org/ontology/MESH/C515057 http://purl.bioontology.org/ontology/MESH/D054339 https://en.wikipedia.org/wiki/Steroidogenic_factor_1 https://www.ncbi.nlm.nih.gov/protein/NP_004950 https://www.uniprot.org/uniprot/F1D8R8 https://www.wikidata.org/wiki/Q21151411 A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes. A transcription factor involved in sex determination by controlling activity of genes related to the reproductive glands or gonads and adrenal glands. This protein is encoded by the NR5A1 gene, a member of the nuclear receptor subfamily, located on the long arm of chromosome 9 at position 33.3. NR5A1 protein SF-1 nuclear receptor 5A1 protein steroidogenic factor 1 nuclear receptor