ACTIVATION GENE ONTOLOGYGO:0004674 Reactome Database ID Release 431014248 Reactome, http://www.reactome.org p-IRAK1:p-IRAK4:oligo-MyD88:activated TLR7/8 or 9 complex Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9