'p-T69,T71-ATF2 [nucleoplasm]' positively regulates 'Expression of PPARGC1A (PGC-1alpha)' ACTIVATION As inferred from mouse, phosphorylated ATF2 binds the PGC-1alpha promoter and enhances expression (Cao et al. 2004, Akimoto et al. 2005, Wright et al. 2007, Akimoto et al. 2008). Intracellular calcium acting via p38 MAPK is believed to activate (phosphorylate) ATF2. Pubmed15024092 Pubmed15767263 Pubmed17488713 Pubmed18434626 Reactome Database ID Release 431606710 Reactome, http://www.reactome.org ReactomeREACT_120337 Expression of PPARGC1A (PGC-1alpha)